The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties

A study of the luminescence properties of alpha-1-acid glycoprotein (α1AAGP) and its basic drug binding properties was carried out. The fluorescence and phosphorescence properties of the protein were studied. The luminescence were found not to differ from those of a typical protein. The effect of ba...

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Main Author: Abdullahi, Gambo L.
Published: Loughborough University 1984
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.350822
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spelling ndltd-bl.uk-oai-ethos.bl.uk-3508222018-08-07T03:17:10ZThe luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding propertiesAbdullahi, Gambo L.1984A study of the luminescence properties of alpha-1-acid glycoprotein (α1AAGP) and its basic drug binding properties was carried out. The fluorescence and phosphorescence properties of the protein were studied. The luminescence were found not to differ from those of a typical protein. The effect of basic drug binding on the α1AAGP fluorescence or the drug fluorescence quantum yield was investigated. Drugs studied were; propranolol, chlorpromazine and imipramine. Only chlorpromazine showed quenching of the protein fluorescence.572BiochemistryLoughborough Universityhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.350822https://dspace.lboro.ac.uk/2134/33134Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 572
Biochemistry
spellingShingle 572
Biochemistry
Abdullahi, Gambo L.
The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties
description A study of the luminescence properties of alpha-1-acid glycoprotein (α1AAGP) and its basic drug binding properties was carried out. The fluorescence and phosphorescence properties of the protein were studied. The luminescence were found not to differ from those of a typical protein. The effect of basic drug binding on the α1AAGP fluorescence or the drug fluorescence quantum yield was investigated. Drugs studied were; propranolol, chlorpromazine and imipramine. Only chlorpromazine showed quenching of the protein fluorescence.
author Abdullahi, Gambo L.
author_facet Abdullahi, Gambo L.
author_sort Abdullahi, Gambo L.
title The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties
title_short The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties
title_full The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties
title_fullStr The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties
title_full_unstemmed The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties
title_sort luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties
publisher Loughborough University
publishDate 1984
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.350822
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