DNA-ligand interactions : a biophysical study of 9-hydroxyellipticine, Hoechst 33258 and a meso-substituted porphyrin derivative binding to DNA

The binding of 9-hydroxyellipticine (9-OHE), Hocchst-33258 (Hoechst) and trans-bis-(4- N-methylpyridiniumyl)diphenylporphyrin (t-112P) to DNA has been studied by means of spectroscopic techniques. The binding modes of t-H2P to calf thymus DNA (ct-DNA), poly[d(G-C)12 and poly[d(A-T)12 were dependent...

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Bibliographic Details
Main Author: Ismail, Matthew Arif
Published: University of Warwick 1998
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326224