Mechanistic studies on isopenicillin N synthase

The mechanism of penicillin formation through the action of the enzyme isopenicillin N synthase (IPNS) on the substrate δ-(L-α-aminoadipoyl)-L-cysteinyl-D-valine and synthetic analogues, still raises many unresolved questions, despite many years' extensive investigation. In order to investigate...

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Bibliographic Details
Main Author: Abbott, Shaun Douglas
Published: University of Oxford 1991
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293446