Protein engineering of human properdin

Properdin is a serum glycoprotein that upregulates the alternative pathway of complement by stabilizing the C3bBb complex. It also binds sulphated glycoconjugates, such as sulphatide, in vitro. Properdin is composed of cyclic dimers, trimers and tetramers of a 53 kDa monomeric subunit. The monomer c...

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Bibliographic Details
Main Author: Higgins, Jonathan M. G.
Other Authors: Reid, Kenneth B. M.
Published: University of Oxford 1994
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260151