Protein engineering of human properdin
Properdin is a serum glycoprotein that upregulates the alternative pathway of complement by stabilizing the C3bBb complex. It also binds sulphated glycoconjugates, such as sulphatide, in vitro. Properdin is composed of cyclic dimers, trimers and tetramers of a 53 kDa monomeric subunit. The monomer c...
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University of Oxford
1994
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260151 |