TGFβ modulated changes in VEGF expression and secretion may enhance disease progression through an autocrine mechanism

Prostate cancer is the most common malignancy in American males, and the second leading cause of cancer deaths. Transformed cells break free of cell cycle regulation and proliferate uncontrollably. Growth factors like TGF-β and VEGF have been linked to enhanced metastasis and tumor neovascularizatio...

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Bibliographic Details
Main Author: Darrington, Eric Brian
Format: Others
Published: DigitalCommons@Robert W. Woodruff Library, Atlanta University Center 2010
Subjects:
Online Access:http://digitalcommons.auctr.edu/dissertations/219
http://digitalcommons.auctr.edu/cgi/viewcontent.cgi?article=1764&context=dissertations