The Role of Mutations in Protein Structural Dynamics and Function: A Multi-scale Computational Approach
abstract: Proteins are a fundamental unit in biology. Although proteins have been extensively studied, there is still much to investigate. The mechanism by which proteins fold into their native state, how evolution shapes structural dynamics, and the dynamic mechanisms of many diseases are not well...
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Format: | Doctoral Thesis |
Language: | English |
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2011
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Online Access: | http://hdl.handle.net/2286/R.I.9515 |