Allosteric Modulation and Structural Determination of G-Protein Coupled Receptors

abstract: G protein-coupled receptors (GPCRs) are known to be modulated by membrane cholesterol levels, but whether or not the effects are caused by specific receptor-cholesterol interactions or cholesterol’s general effects on the membrane is not well-understood. Results from coarse-grained molecul...

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Bibliographic Details
Other Authors: Geiger, James (Author)
Format: Doctoral Thesis
Language:English
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/2286/R.I.63027