Small Molecule Inhibition of Quiescin Sulfhydryl Oxidase 1 (QSOX1), a Dynamic Pro-Tumorigenic Regulator of the Extracellular Matrix

Small Molecule Inhibition of Quiescin Sulfhydryl Oxidase 1 (QSOX1), a Dynamic Pro-Tumorigenic Regulator of the Extracellular Matrix

abstract: Quiescin sulfhydryl oxidase 1 (QSOX1) is a highly conserved disulfide bond-generating enzyme that represents the ancient fusion of two major thiol-disulfide oxidoreductase gene families: thioredoxin and ERV. QSOX1 was first linked with cancer after being identified as overexpressed in panc...

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Bibliographic Details
Other Authors: Hanavan, Paul Daniel (Author)
Format: Doctoral Thesis
Language:English
Published: 2015
Subjects:
Cellular biology
Molecular biology
Biochemistry
Cancer
Invasion
LOPAC1280
QSOX1
Small molecule inhibition
Xenograft
Online Access:http://hdl.handle.net/2286/R.I.36521

Internet

http://hdl.handle.net/2286/R.I.36521

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