Study of Site Specific Cleavage of Strongly Bound Hairpin DNAs by Bleomycin

abstract: Natural products that target the DNA of cancer cells have been an important source of knowledge and understanding in the development of anticancer chemotherapeutic agents. Bleomycin (BLM) exemplifies this class of DNA damaging agent. The ability of BLM to chelate metal ions and effect oxid...

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Bibliographic Details
Other Authors: Segerman, Zachary Jay (Author)
Format: Dissertation
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/2286/R.I.14241