Clinical Course of Rattlesnake Bite Victims Treated without Antivenom
A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine. === The standard treatment for rattlesnake envenomation (RSE) is antivenom. The clinical course of patients treated with antivenom is well d...
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ndltd-arizona.edu-oai-arizona.openrepository.com-10150-6271522018-03-30T03:00:28Z Clinical Course of Rattlesnake Bite Victims Treated without Antivenom Chang, Phoebe The University of Arizona College of Medicine - Phoenix Curry, Steven MD Rattlesnake Anti-Venoms Envenomation A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine. The standard treatment for rattlesnake envenomation (RSE) is antivenom. The clinical course of patients treated with antivenom is well described. Prior to 2000, only a whole IgG AV (IgGAV) associated with high rates of hypersensitivity reactions (HSS) was available to treat RSE. Since 2000, Crotalidae Polyvalent Immune Fab (FabAV), which has a better safety profile than IgGAV, has been primarily used. Patients with RSE may not be treated with AV for a variety of reasons including history or perceived risk of HSS, patient refusal, drug shortage, or clinical impression that AV is not indicated. Research Question: What outcomes are associated with moderate to severe RSEs treated without antivenom? 2018-03-28 Thesis http://hdl.handle.net/10150/627152 http://arizona.openrepository.com/arizona/handle/10150/627152 en_US Copyright © is held by the author. Digital access to this material is made possible by the College of Medicine - Phoenix, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. The University of Arizona. |
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en_US |
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Rattlesnake Anti-Venoms Envenomation |
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Rattlesnake Anti-Venoms Envenomation Chang, Phoebe Clinical Course of Rattlesnake Bite Victims Treated without Antivenom |
description |
A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine. === The standard treatment for rattlesnake envenomation (RSE) is antivenom.
The clinical course of patients treated with antivenom is well described.
Prior to 2000, only a whole IgG AV (IgGAV) associated with high rates of
hypersensitivity reactions (HSS) was available to treat RSE. Since 2000,
Crotalidae Polyvalent Immune Fab (FabAV), which has a better safety profile
than IgGAV, has been primarily used.
Patients with RSE may not be treated with AV for a variety of reasons
including history or perceived risk of HSS, patient refusal, drug shortage, or
clinical impression that AV is not indicated.
Research Question: What outcomes are associated with moderate to severe
RSEs treated without antivenom? |
author2 |
The University of Arizona College of Medicine - Phoenix |
author_facet |
The University of Arizona College of Medicine - Phoenix Chang, Phoebe |
author |
Chang, Phoebe |
author_sort |
Chang, Phoebe |
title |
Clinical Course of Rattlesnake Bite Victims Treated without Antivenom |
title_short |
Clinical Course of Rattlesnake Bite Victims Treated without Antivenom |
title_full |
Clinical Course of Rattlesnake Bite Victims Treated without Antivenom |
title_fullStr |
Clinical Course of Rattlesnake Bite Victims Treated without Antivenom |
title_full_unstemmed |
Clinical Course of Rattlesnake Bite Victims Treated without Antivenom |
title_sort |
clinical course of rattlesnake bite victims treated without antivenom |
publisher |
The University of Arizona. |
publishDate |
2018 |
url |
http://hdl.handle.net/10150/627152 http://arizona.openrepository.com/arizona/handle/10150/627152 |
work_keys_str_mv |
AT changphoebe clinicalcourseofrattlesnakebitevictimstreatedwithoutantivenom |
_version_ |
1718617534603722752 |