Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol
Mitochondrial dysfunction is associated with numerous acute and chronic degenerative diseases. The beta-2 adrenergic receptor (beta(2)AR) agonist formoterol induces mitochondrial biogenesis (MB), but other beta(2)AR agonists, such as clenbuterol, do not. We sought to identify the MB signaling pathwa...
| Main Authors: | , , |
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| Other Authors: | |
| Language: | en |
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NATURE PUBLISHING GROUP
2017
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| Online Access: | http://hdl.handle.net/10150/625746 http://arizona.openrepository.com/arizona/handle/10150/625746 |