Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy

Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy

Importance: Polymorphic expression of drug metabolizing enzymes affects the metabolism of antidepressants, and thus can contribute to drug response and/or adverse events. Pregnancy itself can affect CYP2D6 activity with profound variations determined by CYP2D6 genotype. Objective: To investigate the...

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Bibliographic Details
Main Authors: Bérard, Anick, Gaedigk, Andrea, Sheehy, Odile, Chambers, Christina, Roth, Mark, Bozzo, Pina, Johnson, Diana, Kao, Kelly, Lavigne, Sharon, Wolfe, Lori, Quinn, Dee, Dieter, Kristen, Zhao, Jin-Ping
Other Authors: Univ Arizona, Coll Med, Arizona Pregnancy Riskline
Language:en
Published: FRONTIERS MEDIA SA 2017
Subjects:
CYP2D6 genotypes
antidepressant discontinuation
dosage modification
maternal depression in pregnancy
Online Access:http://hdl.handle.net/10150/625212
http://arizona.openrepository.com/arizona/handle/10150/625212

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