Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus

Psychiatric patients treated with lithium (Li+) may develop nephrogenic diabetes insipidus (NDI). Although the etiology of Li+-induced NDI (Li-NDI) is poorly understood, it occurs partially due to reduced aquaporin-2 (AQP2) expression in the kidney collecting ducts. A mechanism postulated for this i...

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Bibliographic Details
Main Authors: Poulsen, Søren Brandt, Kristensen, Tina Bøgelund, Brooks, Heddwen L., Kohan, Donald E., Rieg, Timo, Fenton, Robert A.
Other Authors: Univ Arizona, Coll Med, Dept Physiol
Language:en
Published: AMER SOC CLINICAL INVESTIGATION INC 2017
Online Access:http://hdl.handle.net/10150/623931
http://arizona.openrepository.com/arizona/handle/10150/623931