Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques

Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques

SIV DNA can be detected in lymphoid tissue-resident macrophages of chronically SIV-infected Asian macaques. These macrophages also contain evidence of recently phagocytosed SIV-infected CD4(+) T cells. Here, we examine whether these macrophages contain replication-competent virus, whether viral DNA...

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Bibliographic Details
Main Authors:	DiNapoli, Sarah R., Ortiz, Alexandra M., Wu, Fan, Matsuda, Kenta, Twigg, Homer L., Hirsch, Vanessa M., Knox, Kenneth, Brenchley, Jason M.
Other Authors:	Univ Arizona, Dept Med
Language:	en
Published:	AMER SOC CLINICAL INVESTIGATION INC 2017
Online Access:	http://hdl.handle.net/10150/623383 http://arizona.openrepository.com/arizona/handle/10150/623383

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