Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression
A growing body of evidence suggests that macrophage polarization dictates the expression of iron-regulated genes. Polarization towards iron sequestration depletes the microenvironment, whereby extracellular pathogen growth is limited and inflammation is fostered. In contrast, iron release contribute...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Language: | en |
| Published: |
PUBLIC LIBRARY SCIENCE
2016
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| Online Access: | http://hdl.handle.net/10150/622409 http://arizona.openrepository.com/arizona/handle/10150/622409 |