Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice

INTRODUCTION:Although the prevalence of arthritis dramatically increases with age, the great majority of preclinical studies concerning the mechanisms that drive arthritic joint pain have been performed in young animals. One mechanism hypothesized to contribute to arthritic pain is ectopic nerve spr...

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Bibliographic Details
Main Authors: Jimenez-Andrade, Juan, Mantyh, Patrick
Other Authors: Department of Pharmacology, University of Arizona, 1501 N. Campbell Avenue, Tucson, AZ 85724, USA
Language:en
Published: BioMed Central 2012
Online Access:Jimenez-Andrade and Mantyh Arthritis Research & Therapy 2012, 14:R101 http://arthritis-research.com/content/14/3/R101
http://hdl.handle.net/10150/610392
http://arizona.openrepository.com/arizona/handle/10150/610392