Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy

Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy

INTRODUCTION:We have previously identified a rare subpopulation of variant human mammary epithelial cells (vHMEC) with repressed p16INK4A that exist in disease-free women yet display premalignant properties, suggesting that they have engaged the process of malignant transformation. In order to gain...

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Main Authors: Dumont, Nancy, Crawford, Yongping, Sigaroudinia, Mahvash, Nagrani, Shefali, Wilson, Matthew, Buehring, Gertrude, Turashvili, Gulisa, Aparicio, Samuel, Gauthier, Mona, Fordyce, Colleen, McDermott, Kimberly, Tlsty, Thea
Other Authors: Department of Pathology and Comprehensive Cancer Center, University of California at San Francisco, 513 Parnassus Avenue, San Francisco, California, 94143-0511, USA
Language:en
Published: BioMed Central 2009
Online Access:http://hdl.handle.net/10150/610113
http://arizona.openrepository.com/arizona/handle/10150/610113

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