Development of MHC Class II Tetramer for Detection of Influenza Specific TCR

T cells play a critical role in adaptive immunity by utilizing genetic recombination to produce diverse TCRs that strongly recognize specific antigens. The TCR recognizes peptides presented by APCs via the MHC class II molecules on their surface. The recognition of a specific peptide stimulates the...

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Bibliographic Details
Main Author: Doig, Cassandra Ann
Other Authors: Frelinger, Jeffrey
Language:en_US
Published: The University of Arizona. 2015
Online Access:http://hdl.handle.net/10150/579393