5-FU Chemotherapy Failure in Some Colorectal Cancer Patients with Microsatellite Instability
Human colorectal cancer (CRC) is the third most commonly diagnosed cancer as well as the second leading cause of cancer mortality in the United States. The hypothesis to be tested in this study is that the loss of TGFβ signaling causes overexpression of the uridine phosphorylase (UP) gene in human C...
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| Language: | en_US |
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The University of Arizona.
2015
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| Online Access: | http://hdl.handle.net/10150/579042 |