Structural Investigations of Gene Promoter Region G-quadruplexes and Their Interactions with Proteins

The discovery of unique, nonduplex structures in the proximal promoter regions of genes controlling cell growth and proliferation has illuminated a new role for DNA in biology. These non-canonical G-quadruplex structures are formed in loosened guanine-rich promoter regions undergoing torsional stres...

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Bibliographic Details
Main Author: Chen, Yuwei
Other Authors: Yang, Danzhou
Language:en_US
Published: The University of Arizona. 2014
Subjects:
Online Access:http://hdl.handle.net/10150/333386

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