COVALENTLY BOUND ORGANOHALOGEN METABOLITES TO LIPID COMPONENTS
Bioactivation of organohalogen xenobiotics produces reactive intermediates which alkylate macromolecules. The activation of carbon tetrachloride, trichloroethylene, and methylene chloride was studied in isolated rat hepatocytes by examining alkylation of lipid, protein, RNA, and DNA. All organohalog...
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Language: | en_US |
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The University of Arizona.
1981
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Online Access: | http://hdl.handle.net/10150/281943 |