Opioid and Non-Opoid Actions of Dynorphin A on Spinal Wide Dynamic Range Neurons
Dynorphin A is an endogenous peptide that can activate opioid receptors and bradykinin receptors; the latter has been proposed to be a mechanism of dynorphin A’s pronociceptive actions. Sensitization of wide dynamic range (WDR) neurons in the spinal dorsal horn causes innocuous stimuli to be perceiv...
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| Language: | en |
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The University of Arizona.
2012
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| Online Access: | http://hdl.handle.net/10150/243876 |