LATERALLY ASSOCIATED PROTEINS MODULATE A6 INTEGRIN CLEAVAGE, A PERMISSIVE PROCESS UTILIZED DURING CANCER METASTASIS
Expression of A6 integrin, a laminin receptor, on tumor cell surfaces is associated with reduced patient survival and increased metastasis in a variety of tumors. In prostate cancer, tumor extra capsular escape occurs in part via laminin coated nerves and vascular dissemination, resulting in clinic...
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| Language: | EN |
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The University of Arizona.
2009
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| Online Access: | http://hdl.handle.net/10150/194361 |