DESIGN, SYNTHESIS, NMR CONFORMATIONAL ANALYSIS AND DOCKING ANALYSIS OF NOVEL MULTIFUNCTIONAL MOLECULES FOR PAIN

Currently, opioids are extensively used in clinical practices in order to treat pain in patients. However, prolonged administration of opioids are not feasible due to the development of side effects especially tolerance, constipation, addiction and dependence. Our drug design is mainly aimed to redu...

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Bibliographic Details
Main Author: Kumarasinghe, Isuru Ransiri
Other Authors: Hruby, Victor J.
Language:en
Published: The University of Arizona. 2010
Subjects:
Online Access:http://hdl.handle.net/10150/193738