Epigenetic Effects of Arsenite in HeLa Cells
Mechanisms of arsenic toxicity are not yet clear. Arsenite has effects on methylation pathways, by decreasing expression of DNA methylases and depletion of S-adenosylmethionine. Histones are DNA packing proteins that regulate gene expression modulating chromatin accessibility. Methylation at Lysine...
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| Language: | EN |
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The University of Arizona.
2007
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| Online Access: | http://hdl.handle.net/10150/193356 |