Structure-activity relationships for mitomycin C and mitomycin A analogues.
A set of 30 mitomycin C and mitomycin A analogues, including 5 new compounds, was screened against 3 different solid human tumor cell lines using the MTT tetrazolium dye assay. A statistically significant correlation among antitumor activity, quinone reduction potential (E½) and the logarithm of the...
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| Language: | en |
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The University of Arizona.
1996
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| Online Access: | http://hdl.handle.net/10150/187488 |