Directed Ortho-Metalation of the Three Methyl Anisoles in Various Media

Directed ortho-metalation (DoM) is a very useful alternative to electrophillic aromatic substitution (EAS) for the synthesis of substituted aromatic compounds. DoM is highly regiospecific providing metalation chiefly in the ortho-position. However, lateral (a-) metalation of an alkyl side-chain and...

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Bibliographic Details
Main Author: Friesen, Carl
Format: Others
Published: TopSCHOLAR® 1996
Subjects:
Online Access:http://digitalcommons.wku.edu/theses/870
http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=1873&context=theses