Substrate Specificity and Structure-Function Analysis of Bacterial Glyoxalase I Enzymes

Substrate Specificity and Structure-Function Analysis of Bacterial Glyoxalase I Enzymes

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The glyoxalase pathway is widespread in both prokaryotic and eukaryotic organisms. This system utilizes two enzymes (glyoxalase I (GlxI) and glyoxalase II (GlxII)) to catalyze the formation of D-lactate from the substrates glutathione (GSH) and methylglyoxal (MG). The latter chemical is a harmful by...

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Bibliographic Details
Main Author: Mullings, Kadia Yvonne
Language:en
Published: 2008
Subjects:
Glyoxalase
Methylglyoxal
Glutathione
Trypanothione
Glutathionylspermidine
Thiol
Fosfomycin
D-lactate
Chemistry
Online Access:http://hdl.handle.net/10012/3938

Internet

http://hdl.handle.net/10012/3938

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