Modulation of DNA repair pathway after CRISPR/Cas9 mediated Double Stranded Break
The CRISPR/Cas9 system has become the predominant tool for genome editing. Targeted modifications can be introduced while repairing double strand breaks (DSBs), induced by the CRISPR/Cas9 system. The DSB is repaired by either non-homologous end joining (NHEJ) or homologous recombination (HR), and th...
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Virginia Tech
2017
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| Online Access: | http://hdl.handle.net/10919/74884 |