Modulation of DNA repair pathway after CRISPR/Cas9 mediated Double Stranded Break

Modulation of DNA repair pathway after CRISPR/Cas9 mediated Double Stranded Break

The CRISPR/Cas9 system has become the predominant tool for genome editing. Targeted modifications can be introduced while repairing double strand breaks (DSBs), induced by the CRISPR/Cas9 system. The DSB is repaired by either non-homologous end joining (NHEJ) or homologous recombination (HR), and th...

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Bibliographic Details
Main Author: Seo, Jooheon
Other Authors: Animal and Poultry Sciences
Format: Others
Published: Virginia Tech 2017
Subjects:
CRISPR-Cas9 system
genetic engineering
modified cell line
gene targeting
repair system
cell cycle
Online Access:http://hdl.handle.net/10919/74884

Internet

http://hdl.handle.net/10919/74884

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