Thermotherapeutic enhancement of infusate distribution during convection enhanced delivery in the brain using fiber-optic microneedle devices
Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults and has a median survival of 13.4 months. Convection enhanced delivery (CED) has shown promise for the treatment of GBM by allowing intratumoral delivery of therapeutics, bypassing the blood brain barrier. A fiberopti...
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Virginia Tech
2015
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| Online Access: | http://hdl.handle.net/10919/51954 |