Structural and Mechanistic Studies on N-Hydroxylating Monooxygenases Involved in Siderophore Biosynthesis

N-Hydroxylating monooxygenases (NMOs) are flavin dependent enzymes that primarily catalyze the hydroxylation of L-ornithine or L-lysine. This is the first, committed step to siderophore biosynthesis. Pathogenic microbes including Aspergillus fumigatus and Mycobacterium tuberculosis secrete these low...

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Bibliographic Details
Main Author: Robinson, Reeder McNeil
Other Authors: Biochemistry
Format: Others
Published: Virginia Tech 2015
Subjects:
Online Access:http://hdl.handle.net/10919/51770