Enediynylacridans: design and synthesis of oxidase triggered diyl progenitors
In 1972, Bergman reported cycloaromatization via 1,4- benzenoid diradicals of enediyne systems. Since 1985, five enediyne fungal products with anticancer antibiotic activity have been structurally elucidated, namely, neocarzinostatin chromophore, the calicheamicins, the esperamicins, the dynemicins,...
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| Format: | Others |
| Language: | en |
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/44945 http://scholar.lib.vt.edu/theses/available/etd-09292009-020332/ |