Upstream and downstream issues in the production of recombinant vitamin K-dependent proteins in the milk of transgenic pigs
The short supply and pathogen safety concerns for plasma-derived therapeutic proteins, such as protein C and Factor IX, have spurred the development of recombinant DNA technology for large-scale, economically feasible production of therapeutic proteins. The mammary gland is unique in its ability to...
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| Format: | Others |
| Language: | en |
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/39172 http://scholar.lib.vt.edu/theses/available/etd-08142006-110134/ |