Correlation Between Computed Equilibrium Secondary Structure Free Energy and siRNA Efficiency
We have explored correlations between the measured efficiency of the RNAi process and several computed signatures that characterize equilibrium secondary structure of the partic- ipating mRNA, siRNA, and their complexes. A previously published data set of 609 exper- imental points was used for the a...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/34643 http://scholar.lib.vt.edu/theses/available/etd-08192009-013737/ |