Disruption of the K-Cl Cotransporter-3 Leads to Severe Peripheral Neuropathy

Mutations in the human K-Cl cotransporter-3 (KCC3) gene lead to a severe neurological disorder called peripheral neuropathy associated with agenesis of the corpus callosum (ACCPN). At the same time as that discovery, the KCC3 knockout mouse was created by our laboratory and was found to drag its hin...

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Bibliographic Details
Main Author: Byun, Nellie Eunjoo
Other Authors: William M. Valentine, DVM, Ph.D.
Format: Others
Language:en
Published: VANDERBILT 2008
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-12132007-190928/