Disruption of the K-Cl Cotransporter-3 Leads to Severe Peripheral Neuropathy
Mutations in the human K-Cl cotransporter-3 (KCC3) gene lead to a severe neurological disorder called peripheral neuropathy associated with agenesis of the corpus callosum (ACCPN). At the same time as that discovery, the KCC3 knockout mouse was created by our laboratory and was found to drag its hin...
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Language: | en |
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VANDERBILT
2008
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-12132007-190928/ |