Regulation of C/EBPbeta1 in transformed mammary epithelial cells and the role of C/EBPbeta1 in oncogene-induced senescence
Overexpression of activated oncogenes such as Ras(V12) in primary cells induces senescence rather than transformation, thus suppressing tumorigenesis. C/EBPbeta is required for Ras(V12)-induced senescence in mouse embryonic fibroblasts. C/EBPbeta is a transcription factor in which three protein isof...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2010
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-12102010-121704/ |