Examining the Efficacy of Antibiotics and the Proteomic Response in the Treatment of Staphylococcus aureus Biofilms Grown In-Vitro.

The proteomic response of Staphylococcus aureus bacteria in a biofilm is examined using MALDI Imaging Mass Spectrometry (IMS) and Liquid-Chromatography Tandem Mass Spectrometry (LC-MS/MS). S. aureus biofilms grown in-vitro and exposed to ampicillin were imaged in order to demonstrate the diffusion p...

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Bibliographic Details
Main Author: Schroeder, Kaitlin Alayna
Other Authors: Richard Caprioli
Format: Others
Language:en
Published: VANDERBILT 2011
Subjects:
Online Access:http://etd.library.vanderbilt.edu//available/etd-11302011-163338/