Understanding Drug Response Dynamics in BRAF-mutated Melanoma Cells
Targeted therapy is an effective standard of care in BRAF-mutated malignant melanoma. However, tumor remission varies unpredictably among patients and relapse is almost inevitable. Surprisingly, most of our current knowledge of tumor recurrence is derived from post-resistant tumor analyses, or singl...
Main Author: | Paudel, Buddhi Bishal |
---|---|
Other Authors: | Kimbery B. Dahlman |
Format: | Others |
Language: | en |
Published: |
VANDERBILT
2018
|
Subjects: | |
Online Access: | http://etd.library.vanderbilt.edu/available/etd-11212017-220336/ |
Similar Items
-
Cellular Metabolism Contributes To Therapeutic Responses in BRAF-Mutated Melanomas
by: Hardeman, Keisha Nicole
Published: (2017) -
Utilizing Systems Level Approaches to Identify Key Mechanisms of Drug Resistance in BRAF Mutated Melanoma
by: Paraiso, Kim H.T.
Published: (2015) -
Differential responsiveness to BRAF inhibitors of melanoma cell lines BRAF V600E-mutated
by: Muna Al Hashmi, et al.
Published: (2020-05-01) -
Electrochemotherapy with bleomycin is effective in BRAF mutated melanoma cells and interacts with BRAF inhibitors
by: Dolinsek Tanja, et al.
Published: (2016-09-01) -
BRAF Mutation Heterogeneity in Melanoma Lesions
by: Kaori Sakaizawa, et al.
Published: (2020-01-01)