The Molecular Basis of Serotype 1 Reovirus Glycan Interactions and the Function of Glycan-Binding in Pathogenesis
Virus-receptor interactions govern the susceptibility of cells to infection and dictate viral tropism in the host. Mammalian reoviruses display serotype-specific neurotropism in newborn mice, with serotype 1 (T1) strains causing hydrocephalus and serotype 3 (T3) strains causing encephalitis. However...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2014
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-11172014-144537/ |