Glutotoxic and Lipotoxic Consequences for Human β Cell Function In Vivo

Diabetes is characterized by excess levels of glucose and lipid in the blood, which have been proposed to directly and negatively impact islet β cells, exacerbating symptoms and promoting disease progression. Our understanding of glucotoxicity and lipotoxicity in human type 2 diabetes is limited, be...

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Bibliographic Details
Main Author: Bryant, Nora Kayton
Other Authors: Wenbiao Chen
Format: Others
Language:en
Published: VANDERBILT 2015
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-10162015-113112/