Glutotoxic and Lipotoxic Consequences for Human β Cell Function In Vivo
Diabetes is characterized by excess levels of glucose and lipid in the blood, which have been proposed to directly and negatively impact islet β cells, exacerbating symptoms and promoting disease progression. Our understanding of glucotoxicity and lipotoxicity in human type 2 diabetes is limited, be...
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Format: | Others |
Language: | en |
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VANDERBILT
2015
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-10162015-113112/ |