SYNTHESIS AND BIOLOGICAL EVALUATION OF DISPYRIN, SYNTHESIS AND DESIGN OF SELECTIVE M4 MUSCARINIC MODULATORS, AND EXPLORATION OF THE TOTAL SYNTHESIS OF PIPERAZIMYCIN A
The content described in detail in this dissertation covers natural product guided drug discovery, traditional hit-to-lead medicinal chemistry and advances in total synthesis. The synthesis and biological evaluation of dispyrin will be discussed in detail, as well as the optimization of its binding...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2010
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-07292010-140837/ |