Using Statistical Learning Methods for Better Spectrum Classification

Shotgun proteomics has become a widely used technology for identifying a large number of peptides and proteins in complex biological samples. However, any single score function from most search algorithms to evaluate the quality of peptide-spectrum matches (PSMs) is not adequate to discriminate betw...

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Bibliographic Details
Main Author: Chen, Yaoyi
Other Authors: Ming Li
Format: Others
Language:en
Published: VANDERBILT 2014
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-07142014-072802/