APPLICATION OF ORGANOCATALYSIS TO THE SYNTHESIS OF PHARMACOLOGICAL RELEVANT SCAFFOLDS: CHIRAL β-FLUOROAMINES AND AZIRIDINES. TOTAL SYNTHESIS OF CARPANONE, POLEMANNONE B & C AND BREVISAMIDE, AND A GENERAL APPROACH FOR THE CONSTRUCTION OF AZABICYCLIC RING-CONTAINING ALKALOIDS
In the field of organocatalysis, the use of small organic molecules has had a significant impact on chemical synthesis, providing a mild and practical alternative to the more conventional metal based catalyst. The selective introduction of fluorine in organic molecules has been shown to enhance bind...
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Language: | en |
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VANDERBILT
2011
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Online Access: | http://etd.library.vanderbilt.edu//available/etd-06272011-200439/ |