BMP signaling regulation by GREMLIN 2 promotes proliferation and differentiation of human iPS cell-derived cardiac progenitors to cardiomyocytes
Heart development depends on coordinated proliferation and differentiation of cardiac progenitor cells, but how the two processes are synchronized is not well understood. The data herein show that the secreted BMP antagonist GREMLIN 2 (GREM2) is induced in cardiac progenitor cells shortly after card...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en |
| Published: |
VANDERBILT
2017
|
| Subjects: | |
| Online Access: | http://etd.library.vanderbilt.edu/available/etd-03272017-212556/ |