Studies toward the total synthesis of (–)-stolonidiol : a small molecule inducer of choline acetyltransferase

The marine diterpene (–)-stolonidiol (1) has been shown to upregulate neuronal levels of acetylcholine. The mechanism through which a small molecule can impart this allosteric-like effect is currently unknown. A laboratory preparation of the natural product was undertaken in order to produce matiera...

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Bibliographic Details
Main Author: Barton, Thomas John
Format: Others
Language:English
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/2152/ETD-UT-2012-05-5237