Transcriptional mechanisms that produce BK channel-dependent 
drug tolerance and dependence

Transcriptional mechanisms that produce BK channel-dependent 
drug tolerance and dependence

Tolerance to anesthetic drugs is mediated partially by homeostatic mechanisms that attempt to restore normal neural excitability. The BK-type Ca2+-activated K+ channel, encoded by the slo gene, plays an important role in this neural adaptation. In Drosophila, a single sedative dose of the organic so...

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Bibliographic Details
Main Author: Li, Xiaolei, Ph. D.
Format: Others
Language:English
Published: 2012
Subjects:
BK channel
Drug tolerance
Drug dependence
Transcription
Online Access:http://hdl.handle.net/2152/ETD-UT-2011-12-4469

Internet

http://hdl.handle.net/2152/ETD-UT-2011-12-4469

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