Highly concentrated, nanoclusters of self-crowded monoclonal antibodies for low viscosity, subcutaneous injections

Delivery of protein therapeutics is restricted to intravenous infusions due to protein-dependent problems including low solubilities, high viscosities, and physical instabilities. The ability to inject high concentrations of proteins via subcutaneous injections would increase accessibility and compl...

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Bibliographic Details
Main Author: Miller, Maria Andrea
Format: Others
Language:English
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/2152/ETD-UT-2011-05-2662