Kinetics and specificity of human mitochondrial DNA polymerase gamma and HIV-1 reverse transcriptase

The human mitochondrial DNA (mtDNA) genome must be faithfully maintained by the mitochondrial DNA replication machinery. Deficiencies in mtDNA maintenance result in the accumulation of mutations and deletions, which have been associated with a number of neuromuscular degenerative disorders including...

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Bibliographic Details
Main Author: Ziehr, Jessica Lea
Other Authors: Johnson, Kenneth Allen
Format: Others
Language:en
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/2152/31296