Kinetics and specificity of human mitochondrial DNA polymerase gamma and HIV-1 reverse transcriptase
The human mitochondrial DNA (mtDNA) genome must be faithfully maintained by the mitochondrial DNA replication machinery. Deficiencies in mtDNA maintenance result in the accumulation of mutations and deletions, which have been associated with a number of neuromuscular degenerative disorders including...
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Format: | Others |
Language: | en |
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2015
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Online Access: | http://hdl.handle.net/2152/31296 |